General Information

  • ID:  hor000925
  • Uniprot ID:  E9GHT8
  • Protein name:  Sulfakinin 2
  • Gene name:  NA
  • Organism:  Daphnia pulex (Water flea)
  • Family:  Gastrin/cholecystokinin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Daphnia (genus), Daphniidae (family), Anomopoda (infraorder), Cladocera (suborder), Diplostraca (order), Phyllopoda (subclass), Branchiopoda (class), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  GO:0005576 extracellular region

Sequence Information

  • Sequence:  DFDDYGHMRF
  • Length:  10
  • Propeptide:  MPIIRQSSVKTLNLLLYIVRVVCAVDGQEEAQQQQQQQHRMKLTMLATVLAAVLVLGVGRATAAPADSSSTATGRRLLHSPNPTSHSKSIDSWLRWLLLRSRIGDKEKTKNGVPSNSFQLARSPVELGSSNPKLQAKLPPAIVQSNDDDETTGFGDEDFADEDVPLVLPEGRQAASKRQPDDYGHMRYGKRDFDDYGHMRFGRR
  • Signal peptide:  MPIIRQSSVKTLNLLLYIVRVVCA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-E9GHT8-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor000925_AF2.pdbhor000925_ESM.pdb

Physical Information

Mass: 146310 Formula: C58H75N15O18S
Absent amino acids: ACEIKLNPQSTVW Common amino acids: D
pI: 4.31 Basic residues: 2
Polar residues: 2 Hydrophobic residues: 2
Hydrophobicity: -124 Boman Index: -3663
Half-Life: 1.1 hour Half-Life Yeast: 3 min
Half-Life E.Coli: >10 hour Aliphatic Index 0
Instability Index: -223 Extinction Coefficient cystines: 1490
Absorbance 280nm: 165.56

Literature

  • PubMed ID:  21830762
  • Title:  Genomics, Transcriptomics, and Peptidomics of Daphnia Pulex Neuropeptides and Protein Hormones